International Journal of
TechnoChem Research

ISSN 2395 - 4248

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NEWS & UPDATION

  • 2017, Volume 3 No 3 of International Journal of TechnoChem Research is released.
  • 2017, Volume 3 No 3 of International Journal of TechnoChem Research is released.

    2017, Volume 3, No 3, of International Journal of TechnoChem Research is released

  • Included in CAS Database, USA [by Chemical Abstracts Service, USA]
  •  International  Journal of TechnoChem Research

    has been selected for inclusion in CAS,USA  by  Chemical Abstracts Service, USA.

  • International Journal of TechnoChem Research
  • International Journal of TechnoChem Research has been selected for inclusion in CAS,USA by Chemical Abstracts Service, USA.

    International Journal of TechnoChem Research has been selected for inclusion in CAS,USA by Chemical Abstracts Service, USA.

ABSTRACT

A Brief Review on Antihypertensive Drug Delivery through Transdermal Patches

S.P.Deshmukh, Dr. N.S.Bhajipale, V.M.Vaidya, A.G.Sinhe

ABSTRACT

TDDS are topically administration of medicaments through the skin for systemic effects at a predetermined and controlled rate in the form of transdermal patches. Transdermal drug delivery of antihypertensive drugs is able to provide optimum amount of drug to control the disease condition along with minimum side effects. The TDDS avoidance of first pass metabolism and other variables associated with the GI tract, such as Hypertension is directly responsible for 57% of all stroke deaths and 24% of all coronary heart disease deaths in India. Oral drug administration is limited by many disadvantages. This review on different antihypertensive drugs showed that, by delivering drug through this route improves bioavailability a well as patient compliance. This can also lead to cost effectiveness of healthcare treatment for the long term management of hypertension. But the main limitation is that, the drug should possess certain specific physicochemical properties which should be suited to permeate through the skin, therefore all antihypertensive drugs cannot be given by this route. Key words: Anithypertensive drug delivery, Transdermal patches.

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